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Home - Products - PI3K/Akt/mTOR signaling - mTOR - CIDD 0067106

CIDD 0067106

CAS No. 2151865-39-1

CIDD 0067106( CIDD0067106 )

Catalog No. M13435 CAS No. 2151865-39-1

CIDD 0067106 is a novel natural product-based diaryloxazole that potent and selective antiproliferative activities against androgen receptor-positive breast cancer cells.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    CIDD 0067106
  • Note
    Research use only, not for human use.
  • Brief Description
    CIDD 0067106 is a novel natural product-based diaryloxazole that potent and selective antiproliferative activities against androgen receptor-positive breast cancer cells.
  • Description
    CIDD 0067106 is a novel natural product-based diaryloxazole that potent and selective antiproliferative activities against androgen receptor-positive breast cancer cells (MDA-MB-453 cell GI50=0.8 uM); displays approximately 37.5- to 62.5-fold antiproliferative selectivity for MDA-MB-453 cells over others TNBC cells (MDA-MB-231 GI50=50 uM); inhibits the activity of the mTORC1 pathway.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    CIDD0067106
  • Pathway
    PI3K/Akt/mTOR signaling
  • Target
    mTOR
  • Recptor
    mTOR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2151865-39-1
  • Formula Weight
    483.99
  • Molecular Formula
    C26H30ClN3O4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(OC)[C@H]1N(CC2=CC=C(C3=NC=C(C4=CC=C(OC/C=C(C)/C)C=C4)O3)N=C2)CCC1
  • Chemical Name
    (S)-Methyl-1-[(6-(5-(4-[(3-methylbut-2-en-1-yl)oxy]phenyl)-oxazol-2-yl)pyridin-3-yl)methyl]pyrrolidine-2-carboxylate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Robles AJ, et al. J Med Chem. 2017 Nov 3. doi: 10.1021/acs.jmedchem.7b01228.
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